Featured Clinical review September 4, 2026 MitraClip or PASCAL? Two-year results of the CLASP IID trial CLASP IID is the first randomized trial to directly compare PASCAL and MitraClip in patients with severe symptomatic degenerative mitral regurgitation at prohibitive surgical risk. At two years, substantial reduction in mitral regurgitation remained sustained with both systems. 04 Sep Est. reading time: 8 min Read article